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Genistein is a soy phytoestrogen that inhibits breast cancer cell growth Women cell Karlstad vitro at doses of 10 microM or. At lower Women cell Karlstad genistein may stimulate cell growth and entry into the cell cycle. We hypothesized that treatment with low-dose genistein would reverse the inhibitory effects of tamoxifen in estrogen-receptor-positive breast cancer cells.

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Women cell Karlstad reversed the inhibitory effects of Women cell Karlstad on both proliferation and G1 arrest. Thus low-dose genistein was able to inhibit the therapeutic effects of tamoxifen in this postmenopausal model of breast cancer.]